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. 2022 Sep;10(18):967. doi: 10.21037/atm-22-3684

Table 3. Risk factors for the development of renal adverse events in multivariable analysis.

Variable β OR (95% CI) P value Forest plot
Cycles of ICI therapy 0.096 1.101 (1.019–1.188) 0.014 Inline graphic
LMR 0.062 1.064 (0.904–1.254) 0.455
AMC −2.496 0.081 (0.005–1.366) 0.081
Distant metastasis 1.046 2.847 (1.07–7.577) 0.036
COPD 0.531 1.701 (0.492–5.885) 0.402
C4 −2.0 0.135 (0.002–7.811) 0.334
Coronary heart disease 0.797 2.219 (0.565–8.715) 0.253
Hypertension 0.726 2.067 (0.78–5.48) 0.144
SCLC 0.043 1.044 (0.271–4.015) 0.95

ICI, immune checkpoints inhibitor; LMR, neutrophil-to-lymphocyte ratio; AMC, absolute monocyte count; COPD, chronic obstructive pulmonary disease; C4, complement C4; SCLC, small cell lung cancer.