Table 3.
Lp(a) levels by atherosclerotic disease history
| Type of event | Patients N=48 135 |
Lp(a) mg/dL Median (IQR) (n=29 765) |
Lp(a) nmol/L Median (IQR) (n=18 370) |
LDL-C mg/dL Median (IQR) (n=47 988) |
| Cardiovascular history | ||||
| MI, n (%) | 37 383 (77.7) | 18.2 (8.0–58.5) | 40.9 (14.8–155.0) | 75.0 (58.0–98.0) |
| Ischaemic stroke, n (%) | 7568 (15.7) | 14.3 (7.0–45.8) | 41.0 (15.0–150.7) | 83.0 (62.0– 112.1) |
| Any PAD | 5925 (12.3) | |||
| Limb artery revascularisation, n (%) | 3475 (7.2) | 19.6 (7.9–62.9) | 54.0 (18.0–175.0) | 77.7 (59.0– 102.0) |
| Leg amputation, n (%) | 421 (0.9) | 26.8 (8.6–80.8) | 41.1 (18.4–162.3) | 78.0 (57.5– 101.0) |
| Symptomatic PAD with ABI ≤0.9, n (%) | 3557 (7.4) | 21.2 (8.0–70.0) | 57.3 (17.9–185.0) | 83.0 (62.0– 111.0) |
| Medical history (n=48 135) | ||||
| Prior MI, n (%) | 35 088 (72.9) | 18.2 (8.0–57.9) | 40.0 (14.5–152.8) | 75.0 (58.0– 97.8) |
| Prior ischaemic stroke, n (%) | 6037 (12.5) | 14.0 (7.0–41.9) | 40.0 (15.0–142.0) | 85.0 (63.8– 114.0) |
| Prior PAD, n (%) | 4433 (9.2) | 21.0 (8.0–66.5) | 50.0 (16.8–171.8) | 83.0 (62.0– 110.0) |
| Multiple events, n (%) | 2577 (5.4) | 18.3 (7.7–69.0) | 54.3 (16.9–182.0) | 76.2 (57.6– 102.5) |
P<0.001 compared with patients with history of MI.
ABI, ankle brachial index; LDL-C, low-density lipoprotein cholesterol; Lp(a), lipoprotein(a); MI, myocardial infarction; PAD, peripheral artery disease.