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. Author manuscript; available in PMC: 2023 Mar 25.
Published in final edited form as: Methods Enzymol. 2022 Mar 25;672:233–260. doi: 10.1016/bs.mie.2022.02.020

Figure 1: G-quadruplex structure.

Figure 1:

(A) Structural representation of a G4 from human telomeric DNA (PDB: 1KF1) that folds into a parallel G4 structure (Parkinson, Lee, and Neidle 2002). The guanines are represented as slabs and colored differently per quartet. G-strands are marked with black arrows in both the structural model and the corresponding DNA sequence. (B) Interactions between the guanines of one quartet and with K+ ion (purple). Hydrogen bonds and ionic interactions are depicted as blue and gray dashed lines, respectively.