Table 1.
Patient characteristics. Values are presented as median (IQR).
Osilodrostat | Metyrapone | Treatment naïve | Controls | P-value | |
---|---|---|---|---|---|
n | 5 | 5 | 23 | 26 | |
Age, years | 43.0 (18.0) | 47.0 (16.0) | 37.0 (13.0) | 31.5 (17.0) | 0.0210 |
BMI (kg/m2) | 29.7 (5.3) | 34.8 (12.5) | 29.3 (10.2) | 26.7 (8.8) | 0.3517 |
UFC (µg/24 h) | 60.8 (152.4) | 42.2 (125.4) | 665 (516) | WRR | 0.0001 |
DST (µg/dL) | 12.4 (11.8) | WRR |
DST, dexamethasone suppression test; UFC, urinary free cortisol; WRR, within reference range.