Table 4.
Probability of an Adverse Reaction After the Booster Dose According to the Presence or Absence of the Same Reaction After the Second Dose
| Adverse Reaction | Corresponding Reactions After Booster Dose | Incidence of a Corresponding Reaction After Booster Dose, % | RR (95% CI) | ||
|---|---|---|---|---|---|
| Present | Absent | ||||
| Local reactions after dose 2 | |||||
| Pain at injection site | Present | 154 | 1 | 99.4 | 1.12 (.89–1.41) |
| Absent | 8 | 1 | 88.9 | Reference | |
| Redness | Present | 14 | 16 | 46.7 | 1.56 (.98–2.48) |
| Absent | 40 | 94 | 29.9 | Reference | |
| Swelling | Present | 45 | 23 | 66.2 | 1.93 (1.39–2.66) |
| Absent | 33 | 63 | 34.4 | Reference | |
| Systemic reactions after dose 2 | |||||
| Fever ≥38.0°C | Present | 21 | 12 | 63.6 | 3.97 (2.48–6.35) |
| Absent | 21 | 110 | 16.0 | Reference | |
| Fatigue | Present | 129 | 14 | 90.2 | 1.35 (1.00–1.84) |
| Absent | 14 | 7 | 66.7 | Reference | |
| Headache | Present | 80 | 19 | 80.8 | 1.46 (1.15–1.85) |
| Absent | 36 | 29 | 55.4 | Reference | |
| Chills | Present | 52 | 18 | 74.3 | 2.00 (1.48–2.68) |
| Absent | 35 | 59 | 37.2 | Reference | |
| Diarrhea | Present | 3 | 17 | 15.0 | 1.14 (.37–3.50) |
| Absent | 19 | 125 | 13.2 | Reference | |
| Muscle pain | Present | 85 | 6 | 93.4 | 1.22 (1.06–1.40) |
| Absent | 56 | 17 | 76.7 | Reference | |
| Joint pain | Present | 59 | 21 | 73.8 | 1.77 (1.33–2.35) |
| Absent | 35 | 49 | 41.7 | Reference | |
Information on vomiting and lymphadenopathy after the second dose were not collected.
Abbreviations: CI, confidence interval; RR, relative risk.