Table 5.
Prognostic factors of a 3-year survival and local recurrence by multivariate analysis (overall cohort)
| Variables | Overall survival HR (95% CI) |
P* | Disease-free survival HR (95% CI) |
P* | Cumulative local recurrence HR (95% CI) |
P* |
|---|---|---|---|---|---|---|
| CEA | / | / | 2.036 (1.069-3.877) | 0.030 | / | 0.059 |
| CA199 | / | 0.062 | / | 0.946 | / | — |
| Postoperative adjuvant chemotherapy | 2.407 (1.056-5.483) | 0.037 | / | 0.067 | / | — |
| With adenomatous polyps | / | 0.058 | / | / | / | — |
| Tumour differentiation | / | 0.125 | / | 0.103 | / | — |
| pN stage | 3.251 (1.856-5.695) | <0.001 | 2.516 (1.689-3.747) | <0.001 | / | 0.233 |
| With lymphovascular invasion | / | 0.369 | / | 0.122 | / | — |
| With extranodal tumor deposits | / | 0.684 | / | 0.383 | / | — |
| With perineural invasion | / | 0.277 | / | 0.079 | 9.275 (2.014–42.721) | 0.004 |
CI indicates confidence interval; HR, hazard ratio
*Cox proportional hazards regression model