TABLE 3.

Results of DNA sequencing of the gG-1 gene indicating sites of mutations in 11 clinical HSV-1 isolates and two laboratory strains, compared with Syn 17⁺

Codon position(s)	Codon	Mutationa	Amino acid substitution	Mutated HSV-1 strain(s)
−9	ATG	ACC	None	KOS 321, F, 1–9, 11
3	CAG	CCG	Q→P	KOS 321, F, 1–9, 11
20	GTC	GTT	None	9
66	ACG	ACA	None	8
76	ATT	ATC	None	KOS 321, F, 1–11
81–82		CCC	Eb	KOS 321, 7
89	GAC	GAT	None	KOS 321, 7
94	GAG	AAG	E→K	KOS 321, 7
108	GGC	GGT	None	KOS 321, 7, 9
111	TTC	GTC	F→V	KOS 321, 7, 9
114	GCT	GCC	None	KOS 321, 7
115	GAG	GGG	E→G	KOS 321, 7, 9
116	GAC	GAT	None	KOS 321, 7
117	GTC	GAC	V→D	KOS 321, 7, 9
119	AAG	AAA	None	KOS 321
121	AAA	AAC	K→N	6
129	TCC	CCC	S→P	KOS 321, 7, 9
131	GAT	GGT	D→G	KOS 321, 7, 9
143	CGC	CGA	None	KOS 321, 7, 9
150	ATT	AGT	I→S	KOS 321, 7
157	CGC	CGA	None	KOS 321, 7
161	CGA	CAA	R→Q	KOS 321, 7
163	ACC	CCC	T→P	KOS 321, 7
166	GGA	GGG	None	KOS 321, 7
204	TTG	GTG	L→V	KOS 321, 7
207	GGT	GTT	G→V	KOS 321, 7
208	GCG	GCT	None	KOS 321
215	GGC	GGT	None	KOS 321, 7
235	TCC	CCC	S→P	KOS 321, 7

^aBoldface type indicates the mutation. 

^bA triple-C insert was detected at this position in two strains.