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. Author manuscript; available in PMC: 2022 Oct 18.
Published in final edited form as: Mol Imaging Biol. 2019 Oct;21(5):852–860. doi: 10.1007/s11307-019-01326-5

Fig. 1.

Fig. 1.

a In vitro testing of MN-EPPT and MN-SCR accumulation in MC38 MUC1 and MC38 neo cell lines. b Cell binding assays showed concentration dependent preferential uptake of experimental MN-EPPT probe by MC38 MUC1cells compared to control probes. There was no difference in uptake between the experimental and control probes by the control MC38 neo cell line. c Fluorescence microscopy of MC38 MUC1cells before (left) and after (right) 5-FU treatment. Note changes in uMUC1 expression and reduced MN-EPPT accumulation in treated cells. (Green - uMUC1; red - Cy5.5 dye conjugated to nanoparticles; blue – DAPI, cell nucleus; magnification bar = 15 μm).