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. 2022 Sep 30;26(3):117–126. doi: 10.12717/DR.2022.26.3.117

Fig. 2. Co-transfection of TSC-22 and BRD7 inhibits tumor cell growth.

Fig. 2.

Ovarian cancer cells were seeded on 24-well culture plates and attached for 24 h. (A) SKOV3 and OVCAR3 cancer cells were transiently transfected with expression vectors encoding TSC-22 and/or BRD7 and the number of survival cells was counted at 1 day intervals for 3 days. (B) SKOV3 cells were transiently transfected with 50 ng pcDNA-BRD7 and various concentrations of pcDNA-TSC-22 (0, 20, 50, 100 ng) or 50 ng pcDNA-TSC-22 and various concentrations of pcDNA-BRD7 (0, 20, 50, 100 ng) and incubated for 48 h and the number of survival cells was counted. Results are means±SD from three samples each. * p<0.05, ** p<0.01, *** p<0.001 compared with control. BRD7, bromodomain-containing protein 7; TSC-22, transforming stimulated clone 22.