Table 3.
Association of TyG Index with MAFLD Risk in Cox Proportional Hazard Models
Variables | Crude Modela | Model 1b | Model 2c | |||
---|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
TyG index | 2.190 (1.755, 2.732) | <0.001 | 1.864 (1.471, 2.363) | <0.001 | 1.784 (1.383, 2.302) | <0.001 |
Q1 (<7.93) | ref | ref | ref | |||
Q2 (≥7.93 to <8.23) | 1.557 (1.013, 2.395) | 0.044 | 1.229 (0.798, 1.893) | 0.350 | 1.235 (0.801, 1.904) | 0.340 |
Q3 (≥8.23 to <8.58) | 2.475 (1.664, 3.681) | <0.001 | 1.858 (1.245, 2.772) | 0.002 | 1.785 (1.192, 2.673) | 0.005 |
Q4 (≥8.58) | 3.038 (2.063, 4.474) | <0.001 | 2.146 (1.450, 3.175) | <0.001 | 2.000 (1.377, 2.992) | 0.001 |
P for trend | <0.001 | <0.001 | <0.001 |
Notes: aAdjusted for none; bAdjusted for sex, age and BMI at baseline; cAdjusted for sex, age, BMI, hypertension, GGT, ALT, AST, LDL-C, low HDL-C, TC and SUA at baseline. All covariates were brought into the model in the form of categorical variables.