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Susceptibilities of β2 mutant parasites to β2 and β5 subunit inhibitors. Each point represents an independent experiment, for a total of three independent biological replicates, with two technical replicates for β2 mutant (214F) and wild type (S214) Ugandan isolates, a laboratory mutant (49E) derived from V1/S K13C580Y, and control strain W2. The histograms show mean IC50s with standard deviations. Significant comparisons are indicated as * <0.5; ** <0.01; and *** <0.001.
