TABLE 1.
Mutations identified in 106 contezolid-resistant strains of M. tuberculosis
Mutation type | No. of strains | Percentage |
---|---|---|
SNPs in mce3Ra | 59 | 55.6 |
Nonsynonymous mutations | 47 | 44.3 |
Nonsense mutations | 12 | 11.3 |
Indels in mce3R | 40 | 37.8 |
Insertion mutations | 11 | 10.4 |
Deletion mutations | 27 | 25.5 |
Multiple variants in mce3R | 2 | 1.9 |
Unknown | 7 | 6.6 |
Total | 106 | 100 |
SNP, single nucleotide polymorphism.