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. 2022 Oct 18;17(10):e0263861. doi: 10.1371/journal.pone.0263861

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© 2022 Nickel et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — (A) Reciprocal titers of SARS-CoV-2 neutralizing antibodies were measured in focus reduction neutralization assay with inhibitor titer 90% (FRNT90). (B) RBD IgGAM signals were determined as sample/calibrator ratios (C) S1 IgG antibodies were quantitatively measured in binding antibody units per milliliter (BAU/ml). (D-E) S1 IgA and IWV (SARS-CoV-2 inactivated whole-virion) titers were determined as sample/calibrator ratios. (F) Fold reduction of SARS-CoV-2 neutralizing antibody titers, RBD IgGAM, S1 IgG, S1 IgA and IWV IgG antibody signals in follow-up vaccine sera calculated as ratio of value on timepoint P1 to timepoint P3.