Figure 3. A, RT-qPCR results showed that Naringin (Nar) downregulated the gene expression of CYP2E1 in primary rat hepatocytes and HepG2 cells. B, Nar upregulated phase II enzymes involved in acetaminophen (APAP) metabolism in hepatocytes and in HepG2 cells. Data are reported as means±SD (n=3). **P<0.01 vs the APAP group (ANOVA).
