Figure 5. Gradient-based mapping of hemispheric asymmetries in the LPFC.

Meta-analysis of inter-hemispheric asymmetries reasserts the left-hemispheric dominance of language and memory and the right-hemispheric dominance of inhibition and sensory processing/monitoring in the LPFC. Positive log-odds ratios indicate evidence in favor of right-hemispheric preference of a topic in a given bin, whereas negative values indicate evidence in favor of left-hemispheric preference of a topic in a given bin. Error bars represent the 95% confidence intervals estimated from 5000 re-runs of the meta-analysis on random sub-samples of the Neurosynth dataset. Each random sub-sample comprises 60% of the studies of the original dataset (around 8623 studies). Topics are ordered from most-left dominant to most-right dominant based on the average of the log-odds ratio values over the five quintile bins.