Table 2.
The data on treatment and prognosis of P-EMC.
| Ref. | Ki-67 | Site | Treatment | Metastasis | Follow-up (month/s) |
|---|---|---|---|---|---|
| [5] | 2-10% | Right main bronchus | Pneumonectomy | No | FOD: 8 mo |
| 1-2% | Lobe bronchus side unstated | Lobectomy | No | FOD: 60 mo | |
| <1% | Left main bronchus | Pneumonectomy | No | FOD: 96 mo | |
| 1-2% | Right upper lobe bronchus | Lobectomy | No | FOD: 84 mo | |
|
| |||||
| [6] | NA | Left upper lobe | Lobectomy | No | FOD: 16 mo |
|
| |||||
| [7] | NA | Right upper lobe | Lobectomy | No | NA |
|
| |||||
| [9] | NA | Right lower segment bronchus | Lobectomy | The biphasic neoplastic cells replaced part of LN | FOD: 12 mo |
|
| |||||
| [11] | <5% | Right main lower bronchus | Lobectomy | No | FOD: 36 mo |
|
| |||||
| [12] | <5% | Right lower lobe | Wedge resection | NA | FOD: 31 mo |
| <5% | Left lower lobe | Wedge resection | NA | FOD: 14 mo | |
| <5% | Right main lobe | Wedge resection | NA | FOD: 13 mo | |
| <5% | Left upper lobe | Wedge resection | NA | FOD: 78 mo | |
| <5% | Right upper lobe | Wedge resection | NA | No recurrence: 5 mo | |
|
| |||||
| [13] | NA | Left lower lobe | Lobectomy | 1 case: infiltrated peribronchial tissue and LN metastasis | FOD: 4 mo |
| NA | Right upper lobe | Lobectomy | FOD: 12 mo | ||
| NA | Left lower lobe | Lobectomy | NA | ||
| NA | Right upper lobe | Lobectomy | FOD: 12 mo | ||
| NA | Left main bronchus | Pneumonectomy | FOD: 4 mo | ||
|
| |||||
| [14] | 10% | Right upper lobe bronchus | NA | Skull metastasis | NA |
|
| |||||
| [15] | NA | Left lower lobe | Lobectomy | No | Recurrence |
| NA | Left upper lobe | Sleeve lobectomy | No | FOD: 75 mo | |
| NA | Left upper lobe | Lobectomy | No | FOD: 33 mo | |
| NA | Right upper lobe | Lobectomy | No | FOD: 1 mo | |
| NA | Trachea | Endobronchial excision | No | FOD: 10 mo | |
|
| |||||
| [16] | <1% | Intermedius bronchus | Bilobectomy | Hilar and subcarinal LN+ | Adjuvant chemotherapy |
|
| |||||
| [17] | NA | Left main bronchus | Pneumonectomy | No | FOD: 72 mo |
| NA | Left lower lobe | Lobectomy | No | FOD: 48 mo | |
| NA | Right lower lobe | Lobectomy | No | NA | |
| NA | Right upper lobe | Lobectomy | No | Died in the immediate postoperative period | |
| NA | Left upper lobe | Lobectomy | No | NA | |
| NA | Right lower lobe | Lobectomy | No | Recurred LN mets after 2 years | |
| NA | Right upper lobe | Lobectomy | No | Recurred after 3 years in trachea and right mainstem bronchus, it was treated with radiation and chemotherapy but rapidly developed mets to right cervical lymph nodes, ribs, vertebra, and left kidney and died | |
| NA | Left lower lobe | Lobectomy | No | NA | |
|
| |||||
| [18] | NA | Right upper lobe bronchus | Lobectomy | No | FOD: 24 mo |
|
| |||||
| [19] | NA | Right main bronchus | Pneumonectomy | No | FOD: 36 mo |
|
| |||||
| [20] | NA | Left lower basal bronchus | Lobectomy | No | FOD: 7 mo |
|
| |||||
| [21] | NA | Right upper lobe bronchus | Endobronchial excision | No | FOD: 13 mo |
|
| |||||
| [22] | NA | Left lower lobe bronchus | Lobectomy | No | NA |
|
| |||||
| [23] | 8% | Left lower lobe bronchus | Pneumonectomy | No | FOD: 34 mo |
|
| |||||
| [24] | <5~20% | Left upper lobe bronchus | Lobectomy | No | FOD: 8 mo |
|
| |||||
| [25] | 0.1~0.5% | Right upper lobe bronchus | Pneumonectomy | No | FOD: 6 mo |
|
| |||||
| [26] | 2.8 | Left main bronchus | Endobronchial excision | No | FOD: 6 mo |
|
| |||||
| [27] | NA | Left main bronchus | Endobronchial excision | No | Recurred bilateral lung lesions |
|
| |||||
| [28] | NA | Left upper lobe | Sleeve lobectomy | No | 1/2 cases: recurrence |
| NA | Left lower lobe | Pneumonectomy | No | ||
|
| |||||
| [29] | 2-3% | Intermedius bronchus | Bilobectomy | No | FOD: 9 mo |
|
| |||||
| [30] | NA | Right main bronchus (2) | Lobectomy (5) | Bone metastases within 3 years (1) | FOD: 60 mo (6) |
| NA | Right upper lobe (1) | Pneumonectomy (1) | |||
| NA | Right lower lobe (2) | Sleeve lobectomy (1) | |||
| NA | Left upper lobe (1) | ||||
| NA | Left lower lobe (1) | ||||
|
| |||||
| [31] | NA | Trachea | Resection of 5 tracheal rings | NA | FOD: 24 mo |
|
| |||||
| [32] | 1.6% | Left basal segment bronchus | Lobectomy | No | FOD: 4 mo |
|
| |||||
| [33] | NA | Left lower lobe | NA | No | FOD: 8 mo |
|
| |||||
| [34] | <5% | Right upper lobe | Wedge resection | No | FOD: 24 mo |
|
| |||||
| [35] | NA | Right middle lobe | NA | NA | NA |
|
| |||||
| [36] | NA | Left upper lobe | Lobectomy | No | No recurrence |
|
| |||||
| [37] | 25% | Right middle lobe | Lobectomy | No | NA |
|
| |||||
| [38] | 10% | Left lower lobe | Lobectomy | No | FOD: 6 mo |
|
| |||||
| [39] | NA | Right main bronchus | Electrocautery snare | NA | NA |
|
| |||||
| [40] | NA | Right middle lobe | Wedge resection | No | FOD: 60 mo |
|
| |||||
| [41] | NA | Left lower lobe | Endobronchial excision | NA | NA |
|
| |||||
| [42] | 10% | Upper trachea | Electrocautery snare | NA | NA |
NA: not available, mo: month/s, LN: lymph node, FOD: free of disease, and number: number of people.