Fig. 5. Actual and predicted RMSD between ARTINA and reference PDB structures.

The predicted RMSD to reference (pRMSD) is calculated from the ARTINA results without knowledge of the reference PDB structure (see “Methods”) and, by definition, always in the range of 0–4 Å. For comparability, actual RMSD values to reference are also truncated at 4 Å (protein 2M47 with RMSD 4.47 Å). The dotted lines represent deviations of ±1 Å between the two RMSD quantities.