Table 2:
Association of prenatal smoking with ANS measures at baseline in combined site analyses (Infants whose mothers did not smoke during pregnancy formed the reference group. Results with p-values <0.01, <0.05, <0.10 are bolded)
| Non-smoker Mean (95%CI) | Quit early Mean difference (95%CI) P value |
Low continuous Mean difference (95%CI) P value |
Moderate to high continuous Mean difference (95%CI) P value |
|
|---|---|---|---|---|
| HR (bpm) | 126.13 (125.41, 126.84) | 1.07 (−0.72, 2.87) (0.24) |
0.096 (−0.88, 1.07) (0.84) |
−0.019 (−1.21, 1.16) (0.97) |
| log10SD-RRi (s) | −1.61 (−1.62, −1.59) | −0.005 (−0.04, 0.02) (0.72) |
0.002 (−0.014, 0.02) (0.20) |
0.02 (−0.001, 0.04)
(0.06) |
| log10RMSSD (s) | −1.95 (−1.96, −1.94) | −0.027 (−0.060, 0.0005) (0.10) |
−0.0002 (0.02, 0.01) (0.98) |
0.015 (−0.007, 0.04) (0.17) |
| Breaths/min | 56.05 (55.29, 56.82) | −1.09 (−3.03, 0.84) (0.26) |
0.79 (−0.25, 1.85) (0.13) |
2.22 (0.95, 3.49)
(0.0006) |
| Systolic blood pressure (mmHg) | 83.12 (81.96, 84.28) | 0.88 (−2.15, 3.91) (0.56) |
0.44 (−1.11, 1.98) (0.57) |
1.24 (−0.65, 3.14) (0.19) |
| Diastolic blood pressure (mmHg) | 50.82 (49.86, 51.77) | 1.44 (−1.03, 3.92) (0.25) |
0.87 (−0.39, 2.14) (0.17) |
1.53 (−0.02, 3.09)
(0.053) |
| Low frequency power of HRV | −5.88 (−5.90, −5.86) | 0.0003 (−0.059, 0.059) (0.992) |
0.002 (−0.029, 0.034) (0.881) |
0.03 (−0.003, 0.07)
(0.075) |
| High frequency power of HRV | −6.83 (−6.85, −6.80) |
−0.077 (−0.14, −0.011)
(0.02) |
0.009 (−0.026, 0.045) (0.59) |
0.04 (−0.0013, 0.085)
(0.057) |
| Ratio of low and high frequency power of HRV | 0.94 (0.92, 0.97) |
0.05 (−0.007, 0.11)
(0.08) |
0.006 (−0.025, 0.038) (0.709) |
0.013 (−0.025, 0.051) (0.504) |
| Quiet sleep | ||||
| HR (bpm) | 120.53 (119.39, 121.67) | −0.49 (−3.15, 2.17) (0.71) |
0.58 (−1.04, 2.19) (0.48) |
1.03 (−1.04, 3.11) (0.32) |
| log10SD-RRi (s) | −1.74 (−1.76, −1.72) |
0.05 (−0.002, 0.10)
(0.06) |
−0.01 (−0.05, 0.02) (0.43) |
0.02 (−0.02, 0.06) (037) |
| log10RMSSD (s) | −1.93 (−1.95, −1.90) | 0.009 (−0.04, 0.07) (0.73) |
−0.017 (−0.05, 0.016) (0.31) |
0.007 (−0.036, 0.051) (0.74) |
| Breaths/min | 45.68 (44.65, 46.72) | −1.78 (−4.19, 0.63) (0.14) |
0.16 (−1.31, 1.63) (0.82) |
1.70 (−0.18, 3.58)
(0.07) |
| Systolic blood pressure (mmHg) | 82.75 (81.13, 84.38) | −0.29 (−4.01, 3.41) (0.87) |
0.72 (−1.52, 2.97) (0.52) |
0.06 (−2.75, 2.87) (0.96) |
| Diastolic blood pressure (mmHg) | 50.17 (48.97, 51.37) | −0.70 (−3.45, 2.03) (0.61) |
−0.21 (−1.87, 1.45) (0.80) |
−1.32 (−3.40, 0.74) (0.21) |
| Low frequency power of HRV | −6.27 (−6.32, −6.21) | 0.12 (0.00074, 0.24) (0.04) |
−0.029 (−0.103, 0.043) (0.424) |
0.056 (−0.036, 0.15) (0.234) |
| High frequency power of HRV | −6.84 (−6.89, −6.80) | −0.04 (−0.149, 0.067) (0.45) |
−0.037 (−0.103, 0.028) (0.26) |
0.028 (−0.055, 0.113) (0.506) |
| Ratio of low and high frequency power of HRV | 0.58 (0.53, 0.63) |
0.117 (−0.003, 0.238)
(0.056) |
0.015 (−0.057, 0.087) (0.68) |
0.039 (−0.054, 0.134) (0.40) |