Table 4:
Association of prenatal smoking with mean changes in cardiorespiratory variables in response to 45° head-up tilts in site combined analyses. (Infants whose mothers did not smoke during pregnancy formed the reference group. Results with p-values <0.01, <0.05, <0.10 are bolded)
Non-smoker Mean (95%CI) | Quit early Mean difference (95%CI) (P value) |
Low continuous Mean difference (95%CI) (P value) |
Moderate to high continuous Mean difference (95%CI) (P value) |
|
---|---|---|---|---|
Active sleep | ||||
Δ sustained HR (bpm) | 2.52 (2.08, 2.96) | 0.56 (−1.64, 0.52) (0.31) |
−035 (−0.95, 0.24) (0.24) |
−0.29 (−1.03, 0.45) (0.44) |
Δ acute HR (bpm) | 22. 98 (22.39, 23.57) | −0.69 (−2.13, 0.75) (0.34) |
1.03 (0.23, 1.83)
(0.01) |
1.22 (0.23, 2.21)
(0.02) |
Δ rMSSD-RRi (s) | −0.57 (−0.80, −0.33) | 0.46 (−0.12, 1.04) (0.12) |
0.35 (0.03, 0.67)
(0.03) |
−0.09 (−0.49, 0.30) (0.64) |
Δ change in breathing (breaths/min) | −3.73 (−4.27, −3.19) | 0.35 (−0.98, 1.68) (0.60) |
0.81 (0.07, 1.54)
(0.03) |
−0.005 (−0.91, 0.90) (0.99) |
Δ systolic blood pressure (mmHg) | −6.04 (−6.76, −5.30) |
3.05 (1.22, 4.89)
(0.001) |
0.68 (−0.29, 1.65) (0.16) |
−0.22 (−1.42, 0.98) (0.72) |
Δ diastolic blood pressure (mmHg) | −6.49 (−7.31, −5.83) |
1.95 (0.31, 3.58)
(0.01) |
0.82 (−0.03, 1.69) (0.06) |
0.08 (−0.98, 1.14) (0.88) |
Quiet sleep | ||||
Δ sustained HR (bpm) | 3.39 (2.82, 3.98) | 0.89 (−0.60, 2.38) (0.24) |
−0.38 (1.19, 0.0.41) (0.34) |
0.34 (−0.65, 1.32) (0.50) |
Δ acute HR (bpm) | 22.39 (21.54, 23.24) |
−1.89 (−4.11, 0.32)
(0.09) |
0.08 (−1.08, 1.24) (0.89) |
0.40 (−1.03, 1.83) (0.85) |
Δ rMSSD-RRi (s) | −1.06 (−1.41, −0.71) |
−0.92 (−1.82, −0.015)
(0.05) |
0.12 (−0.36, 0.61) (0.61) |
0.27 (−0.32, 0.86) (0.36) |
Δ change in breathing (breaths/min) | −3.73 (−4.27, −3.19) | 0.30 (−1.19, 1.79) (0.69) |
−0.36 (−1.17, 0.46) (0.39) |
−0.23 (−1.22, 0.77) (0.65) |
Δ systolic blood pressure (mmHg) | −5.07 (−5.89, −4.25) | −0.19 (−2.38, 2.00) (0.86) |
−0.02 (−1.12, 1.07) (0.97) |
0.37 (−0.95, 1.69) (0.58) |
Δ diastolic blood pressure (mmHg) | −5.83 (−6.53, −5.12) | −0.24 (−2.08, 1.61) (0.80) |
0.34 (−0.57, 1.26) (0.46) |
0.32 (−0.78, 1.43) (0.57) |