Table 2.
Baseline characteristics of the AIS patients with and without HT.
| Variables | Non-HT (n = 182) | HT (n = 182) | P-value |
|---|---|---|---|
| Patient characteristics | |||
| Age (years) | 74.0 (66.0–80.0) | 75.0 (66.0–81.0) | 0.713 |
| Male, n (%) | 101 (55.5%) | 104 (57.1%) | 0.751 |
| BMI (kg/m2) | 24.0 (22.2–26.9) | 22.4 (20.8–25.8) | 0.009 |
| History of stroke, n (%) | 45 (24.7%) | 42 (23.1%) | 0.712 |
| History of atrial fibrillation, n (%) | 17 (9.3%) | 55 (30.2%) | <0.001 |
| History of hypertension, n (%) | 140 (76.9%) | 129 (70.9%) | 0.189 |
| History of diabetes, n (%) | 54 (29.7%) | 53 (29.1%) | 0.908 |
| History of dyslipidemia, n (%) | 4 (2.2%) | 7 (3.8%) | 0.358 |
| Smoking status, n (%) | 0.626 | ||
| Nonsmokers | 132 (72.5%) | 140 (76.9%) | |
| Former smokers | 17 (9.3%) | 14 (7.7%) | |
| Current smokers | 33 (18.1%) | 28 (15.4%) | |
| Current drinking, n (%) | 26 (14.3%) | 30 (16.5%) | 0.561 |
| Biochemistry and vital signs on admission | |||
| Baseline SBP (mmHg) | 154.5 ± 21.2 | 152.9 ± 23.1 | 0.530 |
| White cell count, 109/L | 7.0 (5.8–8.4) | 9.2 (7.1–11.1) | <0.001 |
| Lymphocyte count, 109/L | 1.6 (1.2–2.0) | 1.3 (0.9–1.7) | <0.001 |
| Albumin, (g/L) | 40.0 (37.4–41.9) | 37.5 (34.5–40.4) | <0.001 |
| Fibrinogen (g/L) | 3.4 (2.9–3.8) | 3.6 (2.9–4.3) | 0.017 |
| Creatinine (μmol/L) | 64.9 (54.6–76.7) | 66.7(57.2–83.0) | 0.118 |
| Total cholesterol (mmol/L) | 4.4 (3.7–5.0) | 4.2 (3.4–5.0) | 0.269 |
| Large size of the infarction area, n (%) | 19 (10.4%) | 91 (50.0%) | <0.001 |
| NIHSS on admission, median (IQR) | 4.0 (2.0–8.0) | 11.0 (4.0–18.0) | <0.001 |
| Thrombolytic therapy, n (%) | 26 (14.3%) | 39 (21.4%) | 0.075 |
| Anticoagulants therapy before admission, n (%) | 4 (2.2%) | 15 (8.2%) | 0.010 |
| Antiplatelets therapy before admission, n (%) | 12 (6.6%) | 10 (5.5%) | 0.660 |
| CONUT, median (IQR) | 2.0 (1.0–3.0) | 3.0 (1.0–4.0) | <0.001 |
| Malnutrition | <0.001 | ||
| Normal, n (%) | 88 (49.4%) | 47 (28.1%) | |
| Mild, n (%) | 78 (43.8%) | 89 (53.3%) | |
| Moderate, n (%) | 12 (6.7%) | 28 (16.8%) | |
| Severe, n (%) | 0 (0.0%) | 3 (1.8%) | |
| Stroke mechanisms | <0.001 | ||
| Atherosclerotic, n (%) | 134 (73.6%) | 75 (41.2%) | |
| Cardioembolic, n (%) | 27 (14.8%) | 101 (55.5%) | |
| Lacunar, n (%) | 21 (11.5%) | 0 (0.0%) | |
| Other causes, n (%) | 0 (0.0%) | 6 (3.3%) | |
AIS, acute ischemic stroke; HT, hemorrhagic transformation; BMI, body mass index; SBP, systolic blood pressure; NIHSS, National Institutes of Health Stroke Scale; CONUT, Controlling Nutritional Status Score; and IQR, interquartile range. The bold values indicate the P values to highlight the analysis results.