Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Predicted and observed values pharmacokinetic parameters of 50 mg PTU orally.
| Parameter | Predicted | R (MFE) | T (MFE) | |
|---|---|---|---|---|
| Individual | AUC0-t (ng*h/mL) | 4199.36 | 3837.71 (1.09) | 3770.88 (1.11) |
| Tmax (h) | 1.05 | 1.09 (0.96) | 1.22 (0.86) | |
| Cmax (ng/ml) | 1153.56 | 1308.29 (0.88) | 1187.75 (0.97) | |
| Population | AUC0-t (ng*h/mL) | 4278.05 | 3837.71 (1.11) | 3770.88 (1.13) |
| Tmax (h) | 0.95 | 1.09 (0.87) | 1.22 (0.78) | |
| Cmax (ng/ml) | 1185.04 | 1308.29 (0.91) | 1187.75 (1.00) |
