Figure 1.

Gene tracks showing the genomic loci of previously reported Ipmk SNPs. Two SNPs linked to the incidence of IBD patients were associated with the Ipmk gene. SNP rs12570088 was located at approximately 12 kb downstream of the Ipmk gene,¹⁷ and rs2790216 was located at an intron region between exons 1 and 2 of the Ipmk gene.¹⁸ SNP rs2790216 was associated with active enhancer markers H3K27ac and H3K4me1, and H3K4me3, which recruits splicing machinery. ATAC, assay for transposase-accessible chromatin.