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. 2022 Aug 19;14(6):1235–1256. doi: 10.1016/j.jcmgh.2022.08.004

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

IPMK shows a pan-epithelial expression pattern in mouse intestine. (A and B) Expression level of IPMK was analyzed from 2 previous scRNA-seq studies of mouse small intestine.²⁶^,²⁷ IPMK was expressed comparably within mouse small intestinal epithelium including enterocyte, endocrine, goblet, stem, and tuft cells, except Paneth cells. (C) The data from previous scRNA-seq study of mouse colon epithelium²⁵ were used to draw a t-SNE plot showing the mRNA level of epithelial cell type marker genes. (D) Each cell was clustered by an unsupervised method and annotated with gene expression pattern. (E) A violin plot showing the expression level of IPMK from previously clustered scRNA-seq data. IPMK expression levels also were comparable in mouse colon epithelium.