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. 2022 Oct 5;13:1003614. doi: 10.3389/fphar.2022.1003614

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Copyright © 2022 Ma, Zhou, Yang, Xue, Xie, Li and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of MMXY on retinal autophagy flux in CUMS rats (A,B) Immunofluorescence staining of Beclin1 (green), LC3 (green) and DAPI (blue) of retinas in each group. Scale bars = 50 µm. (C)Representative images of Western blot showing Beclin1 and LC3I/II expression in the retina of each group. GAPDH was used to confirm an equal amount of protein (n = 3). (D,E) Quantitative expression of Beclin1 and LC3II/LC3I in each group. Results are shown as the mean ± SD (n = 3). ^# p < 0.05 and ^## p < 0.01 vs. control group; *p < 0.05 and **p < 0.01 vs. model group.