TABLE 1.

Analyses of lymphocyte subsets in infants with cardiac anomalies with and without chromosome 22q11.2 deletion syndrome

Determination	Results for:				P value	Values for healthy controls
	Patients with chromosome 22q11.2 deletion (n = 19)		Cardiac controls (n = 11)
	Mean	5–95% range	Mean	5–95% range		Mean	5–95% range
Absolute lymphocyte count (cells/mm3)	3,164	2,183–4,142	5,128	3,472–6,784	0.0254	6,700	3,500–13,100
CD3
Cells/mm3	1,625	1,058–2,192	3,907	2,652–5,163	0.0003	4,600	2,300–7,000
%	50.5	42–59	77.1	70–84	<0.0001	72	60–85
CD4
Cells/mm3	1,117	753–1,482	2,749	1,865–3,633	0.0002	3,500	1,700–5,300
%	35.4	29–41	55.1	48–62	0.0001	55	41–68
CD8
Cells/mm3	480	290–670	1,412	894–1,930	0.0001	1,000	400–1,700
%	14.4	12–17	20.6	17–24	0.0083	16	9–23
TCRγδ
Cells/mm3	110	57–162	134	38–230	0.6084
%	2.3	1–4	2.2	1–3	0.8818
CD5/19
Cells/mm3	74	13–134	127	76–179	0.1642	600	300–1,100
%	2.1	1–3	2.8	1–4	0.4021
CD19
Cells/mm3	484	329–638	589	314–863	0.4402	1,000	600–1,900
%	21.5	16–27	12.1	6–18	0.0208	15	4–26
CD16/56
Cells/mm3	835	364–1,305	463	119–807	0.2269	500	200–1,400
%	21.0	14–28	7.8	4–12	0.0112	5	1–38
PHAa
SI	102	55–149	173	52–346	0.1984	587b	416–758
cpm	52,867	31,826–73,908	53,055	35,509–70,601	0.9902	88,179b	54,064–122,294

^an = 13 for the chromosome 22q11.2 deletion group; n = 6 for the cardiac control group. 

^bThese represent results for samples from adult controls run simultaneously with the patient samples.