TABLE 3.

Longitudinal analysis of lymphocyte subsets and function in 10 patients with initial CD3 counts of <1,344 cell/mm³

Determination	Results for patients with chromosome 22q11.2 deletion
	Newborns (n = 10)		1-yr-olds (n = 10)		P valuea
	Mean	5–95% range	Mean	5–95% range
Absolute lymphocyte count (cells/mm3)	2,159	1,548–2,771	4,953	2,962–6,945	0.017
CD3
Cells/mm3	808	530–1,086	1,862	1,119–2,605	0.019
%	33.2	16–50	40.7	32–50	0.343
CD4
Cells/mm3	590	380–800	1,271	808–1,734	0.021
%	29.1	20–39	27.3	21–33	0.625
CD8
Cells/mm3	218	131–305	489	229–748	0.058
%	11.1	6–16	13.2	6–21	0.363
TCRγδ
Cells/mm3	92	10–174	297	122–717	0.221
%	1.6	0.4–3	2.8	1–4	0.046
CD5/19
Cells/mm3	37	9–65	174	69–279	0.026
%	2.2	0.3–5	5.9	2–10	0.062
CD19
Cells/mm3	369	152–586	2,166	1,098–3,235	0.007
%	19.5	9–29	42.8	37–49	<0.001
CD16/56
Cells/mm3	591	125–1,058	845	140–1,550	0.281
%	25.1	8–42	14.4	8–20	0.112
PHA
cpm (n = 13)	59,035	25,345–92,725	32,494	60,260–104,730	0.053
SI (n = 13)	123	39–206	357	262–451	0.009

^aP values < 0.05 are boldfaced.