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. 2022 Oct 19;12:17423. doi: 10.1038/s41598-022-21475-y

Table 2.

Patient characteristics including subpopulations.

Whole population (n = 440) Subpopulation with VV-ECMO treatment (n = 67) Subpopulation without VV-ECMO-treatment (n = 373) Subpopulation with acute neurological symptoms leading to neuroimaging (n = 64) Subpopulation with acute PNIF (n = 17)
Age (years mean, SD) 62 ± 15 54 ± 12 64 ± 15 61 ± 14 61 ± 15
% female 23 10 26 14 18
Prior conditions (mean, range) 2 (0–8) 1.5 (0–6) 2 (0–8) 2 (0–8) 2 (0–5)
Prior conditions specified HTN (46%), CKD (17%), CLD (4%), CHD (9%), CPD (20%), CCD (9%), DM (32%), MAL (8%), OB (26%), DEM (3%), NIC (7%) HTN (33%), CKD (9%), CLD (5%), CHD (9%), CPD (18%), CCD (2%), DM (21%), MAL (3%), OB (39%), DEM (0%), NIC (16%) HTN (48%), CKD (18%), CLD (4%), CHD (32%), CPD (21%), CCD (10%), DM (34%), MAL (8%), OB (24%), DEM (3%), NIC (6%) HTN (36%), CKD (20%), CLD (8%), CHD (30%), CPD (31%), CCD (3%), DM (28%), MAL (11%), OB (38%), DEM (0%), NIC (8%) HTN (41%), CKD (18%), CLD (6%), CHD (24%), CPD (18%), CCD (6%), DM (18%), MAL (6%), OB (35%), DEM (0%), NIC (6%)
% ECMO; mean duration days, SD 15; 28 ± 22 100; 28 ± 22 0

At the time point of Neuroimaging

38; 13 ± 14

At the time point of Neuroimaging

50; 5 ± 3

% IVM; mean duration days, SD 59; 21 ± 19 100; 36 ± 24 42; 15 ± 12

At the time point of Neuroimaging

88; 16 ± 14

At the time point of Neuroimaging

82; 13 ± 11

%RRT 12 19 10 48 65
Mean length of stay on ICU, SD 15 ± 17 15 ± 17 11 ± 10

Up to the time point of Neuroimaging

13 ± 13

Up to the time point of Neuroimaging

13 ± 11

% Death during hospital stay 38 64 34 53 65

HTN hypertension, CKD chronic kidney disease, CLD chronic liver disease, CHD chronic heart disease, CPD chronic pulmonary disease, CCD chronic cerebro-vascular disease, DM diabetes, MAL malignancy, OB obesity defined by body mass index (BMI; kg/m2) ≥ 30, DEM clinically proven dementia, NIC smoking. Smoking is likely to be underreported.