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. 2022 Sep 29;13:1020652. doi: 10.3389/fmicb.2022.1020652

TABLE 1.

The minimum inhibitory concentration (MIC) values of commonly clinical antibiotics and plumbagin against colistin-resistant clinical isolates.

Strains Antibiotics IPM ATM LVX FEP MEM GEN CIP TOB PIP CZA COL PLU

Breakpoints (S–R) 2–8 8–32 1–4 8–32 2–8 4–16 0.5–2 4–16 16–128 8–16 2–4 NA
TL1671 MIC (μg/ml) 2S 8S 1S 8S 0.5S 2S 0.25S 1S 8S 4S 8R >256
TL1736 16R 8S 1S 2S 256R 32R 1I 8I 256R 2S 8R >256
TL2314 4I 16I 2S 16I 4I 8I 0.5S 2S 256R 4S 4R >256
TL2917 16R 32R 2S 16I 256R 8I 0.25S 8I 256R 8I 4R >256
TL2967 16R 128R 16R 32R 128R 8I 8R 8I 256R 16R 4R >256
TL3008 16R 4S 1S 4S 8R 16R 0.5S 4S 8S 4S 64R 128
TL3086 128R 128R 8R 16I 128R 128R 16R 128R 128R 4S 128R >256

MIC, COL-R PA inhibitory concentration; IPM, imipenem; ATM, aztreonam; LVX, levofloxacin; FEP, cefepime; MEM, meropenem; GEN, gentamicin; CIP, ciprofloxacin; TOB, tobramycin; PIP, piperacillin; CZA, ceftazidime/avibactam; COL, colistin; S, Susceptible; I, intermediate; R, resistance. NA is not applicable.