Table E2.
Hemodynamic and laboratory parameters at the time of transcranial Doppler study while on VA-ECMO, with respect to the presence of MES
| No MES (n = 141) | MES (n = 46) | P value | |
|---|---|---|---|
| Systolic blood pressure, mm Hg | 98 (86-114) | 93 (76-110) | .22 |
| Diastolic blood pressure, mm Hg | 62 (52-68) | 60 (52-68) | .52 |
| Mean arterial pressure, mm Hg | 72 (66-82) | 71 (62-77) | .06 |
| Hemoglobin, g/dL | 8.2 (7.7-9.0) | 8.2 (7.6-9.4) | .72 |
| Hematocrit, % | 24.5 (22.8-26.6) | 25.4 (23.1-27.8) | .23 |
| Platelet count, k/μL | 62 (43-94) | 79 (59-97) | .30 |
| Fibrinogen, mg/dL | 292 (212-463) | 300 (211-481) | .77 |
| Activated partial thromboplastin time, s | 48.3 (33.8-69.5) | 51.7 (42.5-70.7) | .35 |
| Arterial blood gas Pco2, mm Hg | 38 (35-42) | 39 (36-45) | .75 |
| Arterial blood gas Po2, mm Hg | 133 (94-202) | 128 (109-221) | .81 |
| Ejection fraction, % | 35 (10-60) | 20 (10-55) | .30 |
| ECMO flow, L/min | 4.3 (3.5-5.0) | 4.5 (4.1-5.2) | .34 |
| ECMO speed, rpm | 3450 (3215-3760) | 3600 (3450-3875) | .06 |
Results presented as N (%) or median (interquartile range) as appropriate. MES, Microembolic signals; Pco2, carbon dioxide tension; Po2, oxygen tension; ECMO, extracorporeal membrane oxygenation; VA-ECMO, venoarterial extracorporeal membrane oxygenation.