TABLE 4.

Multivariate Linear Regression of Indoor Microbial Communities (Nutrient Media) and Selected Dry Eye Signs, Odds Ratio (95% Confidence Interval)

	Corneal Epithelial Disruption		Meibomian Gland Dropout
Variables	Model 1	Model 2	Model 1	Model 2
loge(# colonies)	17.29** (1.63–183.02)	9.61 (0.49–189.88)	23.18** (1.64–327.01)	36.56** (1.15–1,163.72)
Age (y)	1.04*** (1.01–1.07)	1.03 (0.99–1.06)	1.05*** (1.02–1.08)	1.05** (1.01–1.08)
Sex (1 = male; 2 = female)	1.18 (0.54–2.55)	1.17 (0.44–3.10)	0.47* (0.20–1.09)	0.39* (0.15–1.05)
loge(TSP)		1.05 (0.73–1.51)		1.22 (0.81–1.85)
Smoke exposure (0 = no, 1 = yes)		0.87 (0.43–1.76)		1.03 (0.45–2.36)
Allergy status (0 = no, 1 = yes)		0.62 (0.30–1.30)		1.23 (0.50–3.06)
Fish oil supplement (0 = no, 1 = yes)		2.89 (0.66–12.75)		0.83 (0.19–3.71)
Race (1 = white, 0 = otherwise)		0.98 (0.38–2.48)		1.24 (0.46–3.33)
Ethnicity (1 = Hispanic, 0 = otherwise)		1.16 (0.39–3.48)		0.83 (0.28–2.49)
Pet(s) in home (0 = no, 1 = yes)		2.50** (1.14–5.48)		1.47 (0.67–3.22)
Observations	214	162	212	161

TSP = total suspended particles.

^***P < .01

^**P < .05

^*P < .1.

Model 1 adjusts for age and sex; model 2 adjusts for age, sex, log(TSP), smoke exposure, allergy status, and number of observations.