. Author manuscript; available in PMC: 2022 Oct 19.

Published in final edited form as: Am J Ophthalmol. 2020 Oct 14;223:193–204. doi: 10.1016/j.ajo.2020.10.003

TABLE 5.

Multivariate Linear Regression of Indoor Microbial Communities (Soy Media) and Selected Dry Eye Signs, Odds Ratio (95% Confidence Interval)

	Corneal Epithelial Disruption		Meibomian Gland Dropout

Variables	Model 1	Model 2	Model 1	Model 2

log_e(# colonies)	28.07^** (1.78–443.79)	14.12 (0.43–463.29)	39.55^** (1.79–875.15)	67.42^** (1.18–3,864.59)
Age (y)	1.04^*** (1.01–1.07)	1.03 (0.99–1.06)	1.05^*** (1.02–1.08)	1.05^** (1.01–1.08)
Sex (1 = male; 2 = female)	1.18 (0.54–2.55)	1.17 (0.44–3.10)	0.47^* (0.20–1.09)	0.39^* (0.15–1.05)
log_e(TSP)		1.05 (0.73–1.51)		1.22 (0.81–1.85)
Smoke exposure (0 = no, 1 = yes)		0.87 (0.43–1.76)		1.03 (0.45–2.36)
Allergy status (0 = no, 1 = yes)		0.62 (0.30–1.30)		1.23 (0.50–3.06)
Fish oil supplement (0 = no, 1 = yes)		2.89 (0.66–12.75)		0.83 (0.19–3.71)
Race (1 = white, 0 = otherwise)		0.98 (0.38–2.48)		1.24 (0.46–3.33)
Ethnicity (1 = Hispanic, 0 = otherwise)		1.16 (0.39–3.48)		0.83 (0.28–2.49)
Pet(s) in home (0 = no, 1 = yes)		2.50^** (1.14–5.48)		1.47 (0.67–3.22)
Observations	214	162	212	161

TSP = total suspended particles.

^***

P < .01

^**

P < .05

P < .1.

Model 1 adjusts for age and sex; model 2 adjusts for age, sex, log(total suspended particles), smoke exposure, allergy status, and number of observations.