Table 4.

Symptomatic medication for acute headache associated with pediatric migraine

Drug	Usual dosage	Maximum per day
Acetaminophen (syrup/tablet)	10–12.5 mg/kg every 4–6 hr	75 mg/kg
	Age >13 yr: 650 mg every 6 hr	4,000 mg
Ibuprofen (syrup/tablet)	10 mg/kg every 6–8 hr	30 mg/kg
	Age >12 yr: 200–600 mg every 6 hr	2,400 mg
Naproxen sodium (tablet)	5–7 mg/kg every 8–12 hr
	Age >13 yr: 250 mg every 8 hr	1,250 mg
Diclofenac (tablet/injection)	Per oral: 0.3–1 mg/kg every 8 hr	150 mg
	IV, IM: 0.3–1 mg/kg every 12 hr	150 mg
Ketorolaca) (injection)	IV: 0.5 mg/kg	15 mg
	Age >15 yr: 10 mg	60 mg
Prochlorperazine (tablet)	Age >5 yr: 0.25 mg/kg every 8 hr	10 mg
	Age >12 yr: 5–10 mg every 8 hr	30 mg
Domperidone (solution/tablet)	Age >12 yr: 0.25 mg/kg every 8 hr	30 mg
	10 mg every 8 hr
Almotriptan (tablet)	Age >12 yr: 6.25–12.5 mg	25 mg
Sumatriptan/naproxen (tablet)	Age >12 yr: 10 mg/60 mg	85 mg/500 mg

IV, intravenous; IM, intramuscular.

^a)Ketorolac can be administered every 6 hours, but should not be used for more than 2 days.