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. 2022 Oct;74(4):918–932. doi: 10.1124/pharmrev.122.000579

Fig. 1.

Fig. 1

Common experimental designs used in TMS-PET literature. Above is the representation of several different experimental designs used throughout the combined TMS and PET literature included in this review. These designs depict (A) studies examining CBF changes (measured with 15O-H2O) induced by TMS using multiple short TMS-PET sessions, (B) single long session studies mainly used to investigate changes in dopamine receptor availability following TMS protocols, and (C) a standard longitudinal design that is primarily used to measure changes in glucose metabolism using [18F]Fluoro-2-deoxy-D-glucose PET.