Table 3.
The relationship between amount of exercise and risk of myocardial infarction or stroke
| No. of patients | Myocardial infarction | Stroke | |||||
|---|---|---|---|---|---|---|---|
| No. of events | IR (/1,000 PY) | aHR* (95% CI) | No. of events | IR (/1,000 PY) | aHR* (95% CI) | ||
| Non-exercisers | 110,499 | 3,011 | 4.4 | 1 (Reference) | 2,634 | 3.8 | 1 (Reference) |
| Overall exercisers | |||||||
| < 500 MET-min/wk | 11,112 | 302 | 4.3 |
0.91 (0.81–1.03) |
287 | 4.1 |
0.99 (0.88–1.12) |
| 500–999 MET-min/wk | 11,407 | 228 | 3.2 |
0.71 (0.62–0.82) |
222 | 3.1 |
0.80 (0.69–0.91) |
| ≥ 1000 MET-min/wk | 32,824 | 692 | 3.4 |
0.76 (0.70–0.83) |
602 | 3.0 |
0.76 (0.69–0.83) |
| P-value | < 0.001 | < 0.001 | |||||
| Non-exercisers | 110,499 | 3,011 | 4.4 | 1 (Reference) | 2,634 | 3.8 | 1 (Reference) |
| New exercisers | |||||||
| < 500 MET-min/wk | 457 | 11 | 3.8 |
0.89 (0.49–1.61) |
14 | 4.8 |
1.38 (0.82–2.33) |
| 500–999 MET-min/wk | 2,384 | 58 | 3.8 |
0.92 (0.71–1.19) |
35 | 2.3 |
0.66 (0.48–0.93) |
| ≥ 1000 MET-min/wk | 18,215 | 413 | 3.6 |
0.81 (0.73–0.90) |
354 | 3.1 |
0.79 (0.71–0.89) |
| P-value | < 0.001 | < 0.001 | |||||
| Non-exercisers | 110,499 | 3,011 | 4.4 | 1 (Reference) | 2,634 | 3.8 | 1 (Reference) |
| Exercise dropouts | |||||||
| < 500 MET-min/wk | 10,377 | 284 | 4.4 |
0.91 (0.81–1.03) |
269 | 4.1 |
0.99 (0.87–1.12) |
| 500–999 MET-min/wk | 7,520 | 142 | 3.1 |
0.66 (0.56–0.78) |
158 | 3.4 |
0.83 (0.71–0.98) |
| ≥ 1000 MET-min/wk | 1,480 | 18 | 2.0 |
0.51 (0.32–0.81) |
20 | 2.2 |
0.67 (0.43–1.04) |
| P-value | < 0.001 | 0.046 | |||||
| Non-exercisers | 110,499 | 3,011 | 4.4 | 1 (Reference) | 2,634 | 3.8 | 1 (Reference) |
| Exercise maintainers | |||||||
| < 500 MET-min/wk | 278 | 7 | 3.8 |
0.93 (0.44–1.94) |
4 | 2.2 |
0.64 (0.24–1.71) |
| 500–999 MET-min/wk | 1,503 | 28 | 2.9 |
0.68 (0.47–0.98) |
29 | 3.1 |
0.82 (0.57–1.18) |
| ≥ 1000 MET-min/wk | 13,129 | 261 | 3.2 |
0.72 (0.64–0.82) |
228 | 2.8 |
0.72 (0.62–0.82) |
| P-value | < 0.001 | < 0.001 | |||||
*In the adjustment, age, sex, low income, smoking status, alcohol consumption, body mass index, hypertension, diabetes mellitus, dyslipidemia, asthma or COPD, and cancer were included
IR incidence rate, PY person-years, aHR adjusted hazard ratio, CI confidence interval, MET metabolic equivalent of task, COPD chronic obstructive pulmonary disease