Table 1.

Comparison of the clinical features, investigation findings and the treatment response of both patients

	1st Patient	2nd Patient
Clinical Presentation	Right sided upper and lower limb weakness rapidly evolving into quadripareseis with brainstem involvement	Bilateral lower limb paraparesis
CSF Findings	Protein – Elevated CSF Glucose drop (< 50% of blood glucose)- present Cells- No cellular reaction in 1st sample, Significantly increased neutrophils in 2nd sample CSF ADA- Elevated 26U/L	Protein – Elevated CSF Glucose drop(< 50% of blood glucose)- Absent Cells- Elevated lymphocytes CSF ADA- Normal
MRI Spine	Long segment myelitis with contrast enhancement extending up to medulla	Long segment myelitis with contrast enhancement
MRI Brain	1st Report- Normal 2nd Report- linear enhancement along the corticospinal tracts, Contrast enhancement of trigeminal nerves	Normal
CSF Culture	positive for Burkholderia pseudomallei	Negative for Burkholderia pseudomallei
Serum melioidosis antibody	1:320	1:640
Treatment response	Poor clinical response	Excellent clinical response