Table 2.
Main characteristics of the control (Ctrl) and case (Case) sub-populations in the eight cancer type-specific EPIC studies
| BrC study | CRC study | EnC study | KiC study | GBTC study | HCC study | Adv. PrC study | Loc. PrC study | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N = 1088 pairs | N = 1500 pairs | N = 689 pairs | N = 511 pairs | N = 85 pairs | N = 121 pairs | N = 533 pairs | N = 1301 pairs | |||||||||
| Ctrl | Case | Ctrl | Case | Ctrl | Case | Ctrl | Case | Ctrl | Case | Ctrl | Case | Ctrl | Case | Ctrl | Case | |
| Age at blood collection | ||||||||||||||||
| Mean (SD) | 51.8 (8.31) | 51.8 (8.33) | 57.0 (7.58) | 57.1 (7.57) | 54.3 (7.83) | 54.3 (7.84) | 55.8 (8.47) | 55.8 (8.46) | 58.7 (7.13) | 58.7 (7.08) | 59.9 (7.01) | 59.9 (6.98) | 57.6 (7.18) | 57.6 (7.18) | 57.9 (6.80) | 58.0 (6.80) |
| Age at cancer diagnosis | ||||||||||||||||
| Mean (SD) | - - | 60.4 (8.83) | - - | 64.9 (8.18) | -- | 62.7 (8.16) | - - | 64.5 (8.83) | - - | 64.9 (7.60) | - - | 66.1 (7.49) | -- | 66.3 (7.02) | -- | 67.1 (6.36) |
| Sex | ||||||||||||||||
| Female | 1088 (100%) | 1088 (100%) | 769 (51.3%) | 769 (51.3%) | 689 (100%) | 689 (100%) | 197 (38.6%) | 197 (38.6%) | 48 (56.5%) | 48 (56.5%) | 35 (28.9%) | 35 (28.9%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| BMI (kg/m2) | ||||||||||||||||
| Mean (SD) | 25.7 (4.32) | 26.2 (4.80) | 26.5 (3.88) | 27.2 (4.34) | 26.0 (4.29) | 28.2 (5.52) | 26.7 (3.84) | 27.8 (4.47) | 26.9 (4.38) | 27.3 (3.98) | 26.9 (3.72) | 28.4 (4.73) | 26.7 (3.48) | 27.0 (3.20) | 27.5 (3.49) | 27.2 (3.37) |
| Education | ||||||||||||||||
| None | 56 (5.1%) | 62 (5.7%) | 124 (8.3%) | 136 (9.1%) | 67 (9.7%) | 76 (11.0%) | 42 (8.2%) | 34 (6.7%) | 6 (7.1%) | 6 (7.1%) | 6 (5.0%) | 7 (5.8%) | 28 (5.3%) | 32 (6.0%) | 106 (8.1%) | 136 (10.5%) |
| Primary school completed | 397 (36.5%) | 377 (34.7%) | 574 (38.3%) | 526 (35.1%) | 269 (39.0%) | 231 (33.5%) | 184 (36.0%) | 186 (36.4%) | 33 (38.8%) | 39 (45.9%) | 49 (40.5%) | 52 (43.0%) | 160 (30.0%) | 166 (31.1%) | 444 (34.1%) | 411 (31.6%) |
| Technical/professional school | 245 (22.5%) | 254 (23.3%) | 333 (22.2%) | 334 (22.3%) | 124 (18.0%) | 118 (17.1%) | 107 (20.9%) | 109 (21.3%) | 20 (23.5%) | 15 (17.6%) | 31 (25.6%) | 38 (31.4%) | 140 (26.3%) | 127 (23.8%) | 305 (23.4%) | 306 (23.5%) |
| Secondary school | 158 (14.5%) | 178 (16.4%) | 188 (12.5%) | 227 (15.1%) | 100 (14.5%) | 127 (18.4%) | 66 (12.9%) | 72 (14.1%) | 11 (12.9%) | 8 (9.4%) | 11 (9.1%) | 5 (4.1%) | 58 (10.9%) | 59 (11.1%) | 103 (7.9%) | 91 (7.0%) |
| Longer education (incl. University deg.) | 211 (19.4%) | 195 (17.9%) | 241 (16.1%) | 227 (15.1%) | 100 (14.5%) | 100 (14.5%) | 96 (18.8%) | 93 (18.2%) | 15 (17.6%) | 17 (20.0%) | 22 (18.2%) | 17 (14.0%) | 132 (24.8%) | 124 (23.3%) | 306 (23.5%) | 324 (24.9%) |
| Not specified | 21 (1.9%) | 22 (2.0%) | 40 (2.7%) | 50 (3.3%) | 29 (4.2%) | 37 (5.4%) | 16 (3.1%) | 17 (3.3%) | 0 (0%) | 0 (0%) | 2 (1.7%) | 2 (1.7%) | 15 (2.8%) | 25 (4.7%) | 37 (2.8%) | 33 (2.5%) |