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. 2022 Jun 24;42(11):2080–2094. doi: 10.1177/0271678X221109873

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© The Author(s) 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — The Longa (ECA) middle cerebral artery occlusion method aggravates the neurological status in the acute phase of stroke. The neurological score (a), posture, flexion and forelimb placing (b), and motility and gait disturbances (c) before (baseline, BL) and 2 (D2), 9 (D9) and 35 (D35) days after middle cerebral artery occlusion (MCAO) by filament insertion through the common carotid artery (CCA), the external carotid artery (ECA), and in sham-operated (CCA sham and ECA sham) animals. Statistical differences using mixed model ANOVA and Tukey post hoc test for the CCA to ECA group (***) P < 0.001; CCA to CCA sham group (###) P < 0.001; ECA to ECA sham group (†††) P < 0.001. Data presented as median with interquartile range.