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. 2022 Oct 19;21:201. doi: 10.1186/s12943-022-01669-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — The proportions of clinical trials on CAR-T cell therapy targets in hematological malignancies. NHL: non-Hodgkin’s lymphoma; TRBC: T cell receptor β-chain constant domains; HL: Hodgkin’s lymphoma; B-ALL: B-acute lymphoblastic leukemia; BAFF-R: B-cell activating factor receptor; TSLPR: thymic stromal lymphopoietin receptor; T-ALL: T-acute lymphoblastic leukemia; AML: acute myeloid leukemia; WT1: wilms tumor 1; FLT3: FMS-like tyrosine kinase 3; NKG2DL: natural killer group 2 member D ligand; CLL1: C-type lectin like molecule 1; CLL: chronic lymphocytic leukemia; BCMA: B-cell maturation antigen; ROR: receptor tyrosine kinase like orphan receptor; MM: multiple myeloma; SLAMF7: signaling lymphocytic activation molecule F7; GPRC5D: G protein-coupled receptor class-C group-5 member-D