Table 4. Survival comparisons between 6th, 7th, and 8th TNM staging systems for each same stage.
6th TNM system | 7th TNM system | 8th TNM system | 6th TNM vs. 7th TNM | 7th TNM vs. 8th TNM | |||
5-year survival | 5-year survival | 5-year survival | Hazard ratio | Hazard ratio | |||
% | % | % | p | 95% CI | p | 95% CI | |
Stage 1A | 70.9 | 70.9 | 70.9 | 1.000 | - | 1.000 | - |
Stage 1B | 63.1 | 63.3* | 66.4‡ | 0.939 | 0.989 (0.760-1.288) | 0.776 | 0.951 (0.673-1.343) |
Stage 2A | 61.3 | 56.4 | 61.3‡ | 0.303 | 1.242 (0.843-1.828) | 0.274 | 0.816 (0.577-1.153) |
Stage 2B | 49.5 | 51.9* | 54.7‡ | 0.255 | 0.877 (0.697-1.098) | 0.842 | 1.026 (0.812-1.298) |
Stage 3A | 36.8 | 42.5* | 48.0‡ | 0.287 | 0.887 (0.710-1.109) | 0.03 | 0.815 (0.673-0.987) |
Stage 3B | 47.3 | 20.0 | 33.7‡ | 0.02 | 2.682 (0.652-11.037) | 0.218 | 0.531 (0.137-2.054) |
Stage 4 | 31.2 | 20.0 | 20.0 | 0.877 | 0.918 (0.306-2.747) | 1.000 | - |
TNM: Tumor, node, metastasis; CI: Confidence interval; * The 7th TNM staging system showed better survival rate than the 6th TNM staging system in same stage in both staging systems; ‡ The 8th TNM staging system showed better survival rate than the 7th TNM staging system in each same stage in both staging systems; HR >1 for all comparisons of each stage. |