Table 3. Predictors of pulmonary hypertension after atrial septal defect closure.

Variables	Range	Univariable HR		p	Multivariable HR		p
		Median	95% CI		Median	95% CI
Age (increase from)	27 to 46	7.46	4.93-11.27	<0.001	4.76	2.68-8.44	<0.001*
Sex		1.06	0.64-1.74	0.81	0.68	0.40-1.15	0.14
Female
Max diameter (increase from)	16 to 24	2.01	1.54-2.63	<0.001	0.83	0.43-1.61	0.58
Pre TR (increase from mild to severe)		5.90	3.31-10.5	<0.001	0.71	0.33-1.49	0.36
Pre RV basal diameter (increase from)	34 to 46	6.54	4.10-10.44	<0.001	4.78	2.57-8.84	<0.001*
Treatment type (transcatheter)		0.91	0.56-1.50	0.72	0.78	0.41-1.49	0.45
Pre PASP (increase from)	29 to 44	3.27	2.50-4.29	<0.001	1.33	0.75-2.35	0.33
Persistent AF		5.59	3.35-9.33	<0.001	2.18	1.21-3.91	0.009*
HR: Hazard ratio; CI: Confidence interval; TR: Tricuspid regurgitation; RV: Right ventricle; PASP: Pulmonary artery systolic pressure; AF: Atrial fibrillation. Pre: Pre-procedural; * p<0.05.