TABLE 3.
| Attribute or characteristic | Data source: |
||
|---|---|---|---|
| AST instrument | LIS | EHR/CDSS | |
| Data extraction | |||
| Ease of data extraction | Standard data export features with predefined formats, generally simple | Format created by vendor; may need specific module or procedure (simple or difficult depending on the system) | Format created by vendor; may need additional programming or module installation (simple or difficult depending on the system) |
| Availability of patient demographics, patient locations, and specimen source data | Possibly, depending on the AST system and completeness of manual data entry or bidirectional LIS interface | Generally, yes | Yes |
| Availability of suppressed antimicrobial resultsa | Yes | Depends on the configuration. Results from suppressed antimicrobials often missing. | Generally, no |
| Availability of quantitative MIC data | Generally, yes | Generally, yes, if desired. | Generally, yes, if desired |
| Availability of results from offline AST (e.g., gradient diffusion and disk diffusion) | No, unless manually entered | Yes | Yes |
| Capability of removing duplicate AST results | No | Yes | Possibly |
| Data analysis | |||
| Customizability | Low | Moderate to high | Moderate to high |
| Stratification of results by patient details | Possibly, depending on the AST system and completeness of manual data entry or bidirectional LIS interface | Yes | Yes |
| Ability to reanalyze retrospective data using updated breakpoints | No | Possibly, if there are separate fields for MIC or zone value and interpretation. | Possibly, if there are separate fields for MIC or zone value and interpretation. |
| Frequency of data analysis, capability of automation | Generated interactively by the user | Can often be run interactively by the user or automated depending on the system | Can often be run interactively by the user or automated depending on the system |
| Additional support for setup and use | |||
| Additional cost | None, utilizing standard AST system features | Standard features within some systems, but needs creation and customization by others | Standard features within some systems, but needs creation and customization by others |
| Dependency on local informatics resources | No | Yes | Yes |
| Dependence on vendor-defined reports | Yes | Depends on the system capabilities, including predefined and customizable reports. | Depends on the system capabilities, including predefined and customizable reports. |
Applies to AST results available/unavailable based on cascade or selective reporting. AST, antimicrobial susceptibility test; LIS, laboratory information system; EHR, electronic healthcare record; CDSS, clinical decision support system.