1-EBIO |
1-Ethyl-2-benzimidazolidinone |
AP-1 |
activation protein-1 |
BCR |
B cell receptor |
BMMC |
bone marrow-derived mast cells |
CAIA |
collagen antibody-induced arthritis |
CaM |
calmodulin |
CAMBD |
CAM-binding domain |
CaMKIV |
calmodulin kinase IV |
cAMP |
adenosine 3’, 5 cyclic monophosphate |
CHO cells |
Chinese hamster ovary cells |
CIA |
collagen-induced arthritis |
CRE |
cAMP response element |
CVID |
common variable immunodeficiency |
CZ |
chlorzoxazone |
DCs |
dendritic cells |
DC-EBIO |
5, 6-dichloro-1-EBIO |
DMARDs |
disease-modifying anti-rheumatic drugs |
EC50
|
effective concentration producing 50% of maximum response |
FLS |
fibroblast-like synoviocytes |
GC |
glucocorticoids |
H-89 |
N-[2-(4-bromocinnamylamino) ethyl]-5-isoquinoline |
HDAC |
histone deacetylase |
HEK-293 cells |
human embryonic kidney cells |
HNSCC |
head and neck squamous cell carcinoma |
IBMX |
3-isobutyl-1-methylxanthine |
IC50
|
inhibitory concentration (e.g. 50% inhibition of maximum) |
IFN-γ |
interferon-γ |
IGFBP5 |
insulin-like growth factor-binding protein 5 |
IL |
interleukin |
JNK |
c-Jun N-terminal kinase |
KCa3.1 |
intermediate conductance Ca2+-activated K+ channel |
LPS |
lipopolysaccharide |
LZ |
leucine zipper |
MAPK |
mitogen-activated protein kinase |
MCP-1 |
monocyte chemoattractant protein-1 |
MCs |
mast cells |
MGCs |
multinucleated macrophages |
MTMR6 |
myotubularin-related protein 6 |
MTX |
Maurotoxin |
NDPK-B |
nucleoside diphosphate kinase B |
NFATc1 |
nuclear translocation of nuclear factor cytoplasmic 1 |
NF-κB |
nuclear factor-κB |
NMDAR |
anti-N-methyl-D-aspartate-receptor |
NS309 |
6, 7-dichloro-1H-indole-2, 3-dione-3-oxime |
NS6180 |
4-[[3-(trifluoromethyl) phenyl] methyl]-2H-1, 4-benzothiazin-3(4H)-one |
NSAIDs |
non-steroidal anti-inflammatory drugs |
PGAM5 |
phosphoglycerate mutase family 5 |
PGE2 |
prostaglandin E2 |
PHPT-1 |
protein histidine phosphatase |
PI3K |
phosphatidylinositol 3-kinase |
PI3K-C2β |
the class II phosphatidylinositol 3 kinase C2β |
PI(3)P |
phosphatidylinositol 3 phosphate |
PKA |
cAMP-dependent protein kinase |
RA |
rheumatoid arthritis |
RANKL |
receptor activator of nuclear factor-κB ligand |
REST |
repressor element 1-silencing transcription |
SKA-121 |
5-methylnaphtho [2, 1-d] oxazol-2-amine |
SKA-31 |
Naphtho [1, 2-d] thiazole-2-ylamine |
STAT-1 |
signal transducer and activator of transcription 1 |
TNF-α |
tumor necrosis factor-α |
TNF-β1 |
transcriptional growth factor β1 |
TRAM-34 |
1-[(2-chlorophenyl) diphenylmethyl]-1H-pyrazole |
TRIM27 |
tripartite motif containing protein 27 |
ZOX |
zoxazolamide |