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. 2022 Oct 19;35(1):61–71. doi: 10.1007/s40520-022-02271-0

Table 4.

Predictors of greater cognitive deterioration (model 1—MMSEc: score < 16 vs >  = 16) and severity of behavioral and psychological symptoms (model 2—NPI: score <  = 11 vs > 11): simple and multiple logistic regression analysis. The models were adjusted for both the characteristics of the caregivers and the characteristics of the elderly assisted

Models Variables Simple logistic regression analysis Multiple logistic regression analysis
OR [95% CI] p OR [95% CI] p
1.Dependent variable: MMSEc Caregivers NVS Possibility of limited or adequate HL
High likelihood of limited HL 2.62 [1.21; 5.93] 0.017 6.58 [2.05; 24.6] 0.003
Age (years)  ≤ 59
 > 59 0.99 [0.97; 1.02] 0.6 1.00 [0.95; 1.07] 0.89
Gender Male
Female 0.85 [0.43; 1.70] 0.7 0.39 [0.14; 1.01] 0.06
Relationship to care recipient Spouse
Son/daughter 1.81 [0.92; 3.62] 0.087 13.4 [3.05; 73.6] 0.001
Years of schooling  ≥ 13
 < 13 1.39 [0.74; 2.64] 0.3 1.59 [0.64; 4.06] 0.32
Mini-Cog Negative
positive 2.46 [0.71; 8.54] 0.16 5.40 [1.15; 29.7] 0.04
Older adults NPI  ≤ 11
 > 11 2.39 [1.26; 4.61] 0.054 1.80 [0.81; 4.01] 0.15
ADL  ≥ 3
 < 3 3.89 [2.04; 7.61] 0.001 4.92 [2.26; 11.2]  < 0.001
2.Dependent variable: NPI Caregivers NVS Possibility of limited or adequate HL
High likelihood of limited HL 2.42 [1.08; 5.89] 0.039 1.89 [0.66; 5.59] 0.2
Age (years)  ≤ 59
 > 59 1.02 [0.99; 1.05] 0.2 0.99 [0.94; 1.04] 0.8
Gender Male
Female 0.84 [0.42; 1.65] 0.6 1.16 [0.49; 2.70] 0.7
Relationship to care recipient Spouse
Son/daughter 0.79 [0.40; 1.54] 0.5 0.81 [0.23; 2.80] 0.7
Years of schooling  ≥ 13
 < 13 1.67 [0.88; 3.24] 0.12 1.45 [0.65; 3.28] 0.4
Mini-Cog Negative
Positive 1.65 [0.47; 72] 0.43 1.67 [0.39; 8.85] 0.5
Older adults MMSEc  ≥ 16
 < 16 2.39 [1.25; 4.55] 0.008 1.85 [0.85; 4.09] 0.12
ADL  ≥ 3
 < 3 2.05 [1.09; 3.92] 0.027 2.09 [1.00; 4.42] 0.051

MMSEc mini mental state examination corrected according to age and education, NVS newest vital sign, NPI neuro-psychiatrics inventory, GDS global deterioration Scale, ADL activities of daily living, OR odds ratio; variance inflation factor < 5