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. 2022 Oct 19;12(46):29983–29990. doi: 10.1039/d2ra03358e

Cytotoxic activity results of the isolated compounds and the extract from C. cylindracea Sonder (IC50).

Cell lines
CCD-1079Sk MDA-MB-231 MCF7
24 h 48 h 24 h 48 h 24 h 48 h
C. cylindracea extracta 465.87 ± 1.87 295.91 ± 0.25 369.12 ± 1.18 245.45 ± 0.24 346.58 ± 2.56 217.64 ± 0.65
Caulerpin 77.44 ± 0.12 36.2 ± 0.69 11.85 ± 1.03 14.68 ± 0.51 15.68 ± 0.38 13.82 ± 0.72
Monomethyl caulerpinate 424.6 ± 0.47 53.97 ± 0.86 13.96 ± 0.52 20.59 ± 0.92 16.82 ± 1.12 17.28 ± 1.32
Doxorubicin 284.5 ± 0.04 62.8 ± 0.06 42.39 ± 0.08
a

IC50 value is calculated as μg mL−1 for only the extract, for the others given as μM.