Cytotoxic activity results of the isolated compounds and the extract from C. cylindracea Sonder (IC50).
| Cell lines | ||||||
|---|---|---|---|---|---|---|
| CCD-1079Sk | MDA-MB-231 | MCF7 | ||||
| 24 h | 48 h | 24 h | 48 h | 24 h | 48 h | |
| C. cylindracea extracta | 465.87 ± 1.87 | 295.91 ± 0.25 | 369.12 ± 1.18 | 245.45 ± 0.24 | 346.58 ± 2.56 | 217.64 ± 0.65 |
| Caulerpin | 77.44 ± 0.12 | 36.2 ± 0.69 | 11.85 ± 1.03 | 14.68 ± 0.51 | 15.68 ± 0.38 | 13.82 ± 0.72 |
| Monomethyl caulerpinate | 424.6 ± 0.47 | 53.97 ± 0.86 | 13.96 ± 0.52 | 20.59 ± 0.92 | 16.82 ± 1.12 | 17.28 ± 1.32 |
| Doxorubicin | 284.5 ± 0.04 | — | 62.8 ± 0.06 | — | 42.39 ± 0.08 | — |
IC50 value is calculated as μg mL−1 for only the extract, for the others given as μM.