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. 2022 Oct 10;40(10):1111–1127.e9. doi: 10.1016/j.ccell.2022.08.014

Figure 5.

Figure 5

Low HRH1 expression is associated with better survival, and antihistamine treatment is prognostic in GBM patients

(A and B) Kaplan-Meier overall survival (A) and progression-free survival (B) analyses of TCGA GBM cohort analyzed with the AffyU133a expression array (n = 539). The blue and yellow shades correspond to the 95% confidence intervals. Patients were split by median expression. p values were calculated based on the Cox proportional hazard model.

(C) Kaplan-Meier estimate of the overall survival of GBM patients from a single center who received antihistamine treatment (n = 29, blue curve) or not (n = 226, yellow curve). The shades correspond to the 95% confidence intervals. The analysis was performed with the Mantel-Cox log-rank test.