Figure 3.

Cell Specific genetic effects on gene expression. (A) Cells within the endometrium, such as the mesenchymal stem cells, undergo proliferation and maturation each menstrual cycle to generate a mature cell. (B) Maturation is controlled by a programmed course of gene expression that results in cell specific properties and are reflected in alteration in the active transcription. (C) In combination and across the genome these active change in expression will induce distinct genome wide gene expression profiles. (D) Genetic effects on transcription therefore will ultimately induce differing effects as the cells mature. Created with BioRender.com.