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. 2022 Jan 26;1:774300. doi: 10.3389/fbinf.2021.774300

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Copyright © 2022 Schmid, Knote, Mück, Pfeiffer, von Mammen and Fischer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Screenshot of the interactive application Alvin. (1) Model parameters are grouped in categories and can be configured by the user. Colors and information text provide possible real-world interpretation of the values. (2) Animated simulation of an alveolus for the active parameter set provides visualization of the effect of the model parameter values. (3) To increase exploratory value, multiple simulation instances can be compared. (4) Quantitative simulation output is displayed with plots color-coded for each active instance of the simulation. (5) Simulation time is displayed and can be reset. (6) Utility functions and settings are available.