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. 2015 Jul 29;2015(7):CD007373. doi: 10.1002/14651858.CD007373.pub3

Comparison 8. Lidocaine 2% gel 6 mL versus placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Mean pain score 20 minutes post‐insertion 1 145 Mean Difference (IV, Fixed, 95% CI) ‐0.80 [‐8.81, 7.21]
2 Side effects or adverse events 1   Odds Ratio (M‐H, Fixed, 95% CI) Subtotals only
2.1 Moderate or severe nausea 1 145 Odds Ratio (M‐H, Fixed, 95% CI) 0.19 [0.02, 1.68]
2.2 Moderately or severely dizzy 1 145 Odds Ratio (M‐H, Fixed, 95% CI) 0.39 [0.07, 2.07]
3 Satisfaction or acceptability 1   Odds Ratio (M‐H, Fixed, 95% CI) Subtotals only
3.1 Amount of pain was mostly or completely acceptable 1 143 Odds Ratio (M‐H, Fixed, 95% CI) 1.06 [0.50, 2.25]