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. 2022 Oct 5;9:993091. doi: 10.3389/fmed.2022.993091

TABLE 3.

Literature review and our series of subdiaphragmatic bronchogenic cysts.

Total (n = 126) Literature (n = 107) Our series (n = 19) p value
Age, years n = 126 n = 107 n = 19 0.261
  Median 41.0 41.0 44.0
  IQR 30.0–51.0 27.0–51.0 35.0–46.5
  Range 0.0–81.0 0.0–81.0 29.0–65.0
Sex n = 126 n = 107 n = 19 0.008
  Male 62 (49.2%) 58 (54.2%) 4 (21.1%)
  Female 64 (50.8%) 49 (45.8%) 15 (78.9%)
Country n = 126 n = 107 n = 19
  Asia 87 (69.0%) 68 (63.6%) 19 (100%)
      China 44 (34.9%) 25 (23.4%) 19 (100%)
  Europe 21 (16.7%) 21 (19.6%) 0 (0%)
  North America 12 (9.5%) 12 (11.2%) 0 (0%)
  Oceania 3 (2.4%) 3 (2.8%) 0 (0%)
  South America 2 (1.6%) 2 (1.9%) 0 (0%)
  Africa 1 (0.8%) 1 (0.9%) 0 (0%)
Symptoms n = 122 n = 103 n = 19
  Asymptomatic 58 (47.5%) 44 (42.7%) 14 (73.7%) 0.013
  Symptomatic 64 (52.5%) 59 (57.3%) 5 (26.3%) 0.013
      Abdominal pain/flank pain 38 (31.1%) 35 (34.0%) 3 (15.8%)
Cyst number n = 126 n = 107 n = 19 0.761
  1 cyst 122 (96.8%) 103 (96.3%) 19 (100%)
  2 cysts 2 (1.6%) 2 (1.9%) 0 (0%)
  3 cysts 1 (0.8%) 1 (0.9%) 0 (0%)
  4 cysts 1 (0.8%) 1 (0.9%) 0 (0%)
Cyst size, cm n = 130 n = 111 n = 19 0.462
  Median 5.0 5.0 5.1
  IQR 3.5–7.1 3.5–7.3 3.6–6.6
  Range 1.5–18.9 1.5–18.9 2.5–9.4
Cyst localization n = 130 n = 111 n = 19
  Left abdomen 100 (76.9%) 85 (76.6%) 15 (78.9%) 0.892
  Midline 12 (9.2%) 10 (9.0%) 2 (10.5%) 0.892
  Right abdomen 18 (13.8%) 16 (14.4%) 2 (10.5%) 0.892
  Upper abdomen 121 (93.1%) 105 (94.6%) 16 (84.2%) 0.126
  Lower abdomen 9 (6.9%) 6 (5.4%) 3 (15.8%) 0.126
  Retroperitoneal 101 (77.7%) 85 (76.6%) 16 (84.2%) 0.564
  Intra-abdominal 29 (22.3%) 26 (23.4%) 3 (15.8%) 0.564
  Left adrenal region 47 (36.2%) 40 (36.0%) 7 (36.8%)
  Pancreatic region 15 (11.5%) 12 (10.8%) 3 (15.8%)
  Gastric cardia/lesser curvature of stomach 12 (9.2%) 9 (8.1%) 3 (15.8%)
Enhancement on CT/MRI n = 69 n = 50 n = 19 0.375
  No 49 (71.0%) 37 (74.0%) 12 (63.2%)
  Yes 20 (29.0%) 13 (26.0%) 7 (36.8%)
Surgical procedure n = 91 n = 72 n = 19
  Laparoscopy 58 (63.7%) 42 (58.3%) 16 (84.2%)
  Laparotomy 25 (27.5%) 23 (31.9%) 2 (10.5%)
  Robotic surgery 2 (2.2%) 2 (2.8%) 0 (0%)
  Thoracotomy 2 (2.2%) 2 (2.8%) 0 (0%)
  VATS 2 (2.2%) 1 (1.4%) 1 (5.3%)
Follow-up time for recurrence, months n = 45 n = 33 n = 12
  Median 12 12 19
  IQR 6–24 6–24 7–30
  Range 1–77 2–49 1–77

Unpaired t-test or Pearson’s chi-square test was employed when appropriate. CT, computed tomography; IQR, interquartile range; MRI, magnetic resonance imaging; VATS, video-assisted thoracoscopic surgery.