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. 2021 Apr 27;1:662210. doi: 10.3389/fbinf.2021.662210

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Copyright © 2021 James, Filby, Brown, Summers, Francis and Rees.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Experimental and model cpF results for cell populations treated with different inhibitor drugs. Experimental (light blue bars) and model (dark blue bars) cpFs after 48 h, after introducing therapeutics; (A) Nocodazole (B) Demecolcine (C) 5-Fluorouracil (D) Etoposide at 32 h. Error bars on experimental data show the largest percentage error for any population observed in the control data. Error bars on model data show standard error from fits of 100 in-silico cell populations.